Northwest Botanicals,Inc.
SPECIALIZING IN MARKETING, PROCESSING, AND COTTAGE INDUSTRIES
1212 SW 5th Street
Grants Pass, OR 97526-6104

(541) 476-5588
(541) 476-1823 (FAX)

05-27-03



SYNEPHRINE EXTRACT   (C9H13NO2)
(Citrus aurantium Link)

Bitter Orange, also known as Seville Orange was known to the early Greeks, and was probably the first orange grown in Europe (twelfth century).  The unripe peel contains appreciable quantities of neohesperidin (14%), and five adrenergic amines (synephrine, N-methyltyramine, hordenine, ocdtopamine, and tyramine).

Synephrine is a well known bronchial dilator, and is used extensively in with diet pills and weight loss formulas.  It also serves as a substitute for ephedrine and caffeine.  Its primary use in the trade is to treat chest congestion and indigestion, stimulate gastrointestinal functions, and improve circulatory and liver functions.

It has been clinically shown that the combination of these adrenergic amines stimulate beta-3 receptors with minimal impact on other receptor sites.  This functions to increase the metabolic rate without affecting heart rate or blood pressure.  They release adrenaline and noradrenaline only in the beta-3 receptor sites (mostly adipose tissue and the liver).  It does NOT cross the blood-brain barrier.

Stimulation of the beta-3 receptor sites elicits the breakdown of lipolysis (fat).  Simultaniously, this stimulation increases the metabolic rate (thermogenesis), which burns calories.  Synephrine offers all the advantages of a stimulant, without the drawbacks.  It functions to burn fat, increase physical performance, and build lean muscle mass.

As existing thermogenics (such as ma huang) come under scrutiny from the FDA and state regulators, the natural products industry is in dire need of a new weight loss/fitness ingredient.  Synephrine functions in three specific ways: it burns fat, increases physical performance, and helps build lean muscle mass.

Northwest Botanicals, Inc is pleased to announce an exclusive relationship with a primary extractor who cultivates the Bitter Orange. Each batch has a certificate of analysis, and is sold in powder extract form. Synephrine extract is available at 4% min., 6% min., 8% min., 10% min., 30% min., and 95% max. (requires special handling)

Price:

Citrus aurantium Extract (Synephrine 4% min.)
$10.00/kg.
500 kg. min. per shipment
Citrus aurantium Extract (Synephrine 6% min.)
$12.50/kg.
500 kg. min. per shipment
Citrus aurantium Extract (Synephrine 8% min.)
$16.50/kg.
500 kg. min. per shipment
Citrus aurantium Extract (Synephrine 10% min.)
$21.50/kg.
500 kg. min. per shipment
Citrus aurantium Extract (Synephrine 30% up.)
$65.00/kg.
200 kg. min. per shipment
Citrus aurantium Extract (Synephrine 95% )

$520.00/kg.

25 kg. min. per shipment
 
Hespiridine (heavy)
$6.50/kg.
FOB CA 1,000 kg. min.
Hespiridine (light)
$8.00/kg.
FOB CA 1,000 kg. min.

*Prices above are all based on FOB Synetch warehouses (LA/NY);
**NBI 5% commission included.

 

CONTACT: Richard Alan Miller,
Agricultural Consultant.


03-02-01

Synephrine,  C9H13NO2
100% Herbal Extract

(Citrus aurantium Extract)

Raw Material:   The dried small fruit of Citrus aurantium

Molecular Formula:   C9H13NO2

Molecular Weight:   176.2

Structure Formula:

Description of Affect:

The pharmacological action of Synephrine include decongestant effects on respiratory system, helpful in the maintenance of normal levels of blood pressure, and it is the most powerful fat loss stimulant.
 

ITEM
STANDARDS
Appearance Positive
Loss on Drying NMT 5.0%
Synephrine Content <HPLC> 4.0%, 6.0%, 8.0%, 10.0%, 30% and above
Particle Size 80-mesh USS 
Sulphated NMT 3.0%
Heavy Metals NMT 20 PPM
Aerobic Plate Count NMT 2000/g 
E. Coli Negative
Salmoscila Negative
Packaging 5-kg/bag
25-kg/drum (0360mm x 500 mm)

CONTACT:     Richard Alan Miller
                    Agricultural Consultant.